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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
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Current Trends in Nursing I01:28

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Infection01:20

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When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
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[2019-nCoV: new challenges from coronavirus].

H Y Tian1

  • 1State Key Laboratory of Remote Sensing Science/College of Global Change and Earth System Science, Beijing Normal University, Beijing 100875, China.

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PubMed
Summary
This summary is machine-generated.

The novel coronavirus (2019-nCoV) outbreak presented significant public health challenges. Research is underway for diagnostics, treatments, and vaccines, highlighting the need for a robust coronavirus surveillance network.

Keywords:
2019-nCoVCoronavirusPublic health

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Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Background:

  • The emergence of the novel coronavirus (2019-nCoV) in Wuhan, China, led to a severe pneumonia outbreak.
  • 2019-nCoV, a β genus Coronavirus related to SARS-CoV and MERS-CoV, causes severe respiratory illness.

Purpose of the Study:

  • To summarize the initial understanding of the 2019-nCoV outbreak.
  • To highlight the scientific response and implications for future surveillance.

Main Methods:

  • Literature review and synthesis of early observational data on 2019-nCoV.
  • Analysis of viral characteristics, transmission, and potential therapeutic targets.

Main Results:

  • 2019-nCoV exhibits weaker pathogenesis than SARS-CoV but has higher transmission competence.
  • The virus may utilize angiotensin-converting enzyme II (ACE2) for cross-species transmission, similar to SARS-CoV.
  • Chinese scientists are actively developing diagnostic reagents, identifying pathogen characteristics, screening drugs, and creating vaccines.

Conclusions:

  • The 2019-nCoV outbreak underscores the critical need for a systematic coronavirus surveillance network.
  • Effective prevention, control, and rapid scientific response are crucial for emerging epidemics.