Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

2.5K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
2.5K
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

645
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
645
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

2.4K
The pathophysiology of pneumonia involves the following steps:
2.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Disseminated Mycobacterium bovis-BCG Infection Following Intravesical BCG Administration in Solid Organ Transplant Recipients.

Transplant infectious disease : an official journal of the Transplantation Society·2026
Same author

Chest CT Findings of <i>Pneumocystis jirovecii</i> Pneumonia in a Large Cohort of Patients Who Are Immunocompromised.

Radiology. Cardiothoracic imaging·2026
Same author

Cutaneous Rosai-Dorfman Disease Misdiagnosed as Granulomatous Dermatitis: A Diagnostic Pitfall.

Cureus·2026
Same author

Impact of positive donor blood cultures on solid organ transplant recipient outcomes.

Infection control and hospital epidemiology·2026
Same author

<i>Pneumocystis jirovecii</i> Pneumonia: Typical and Atypical CT Findings in a Large Cohort of Immunocompromised Patients with and without HIV.

Radiology. Cardiothoracic imaging·2026
Same author

Fear, Feeding, and the Gut: Nutrition Support Considerations in Adults with ARFID and Gastrointestinal Symptoms.

Nutrients·2026
Same journal

Canaliculitis associated with multiple retained silicone punctal plugs and concurrent biodegradable plug placement.

BMJ case reports·2026
Same journal

Bilateral vocal cord paralysis in multifocal motor neuropathy.

BMJ case reports·2026
Same journal

Multiple visceral artery aneurysms and type II Abernethy malformation in a patient with autoimmune hepatitis.

BMJ case reports·2026
Same journal

Congenital nasolacrimal duct cyst complicating as an orbital abscess.

BMJ case reports·2026
Same journal

Management of <i>Achromobacter xylosoxidans</i> bacteraemia with an atypical antimicrobial resistance pattern.

BMJ case reports·2026
Same journal

Unintentional chronic acetaminophen overuse as an under-recognised cause of liver injury.

BMJ case reports·2026
See all related articles

Related Experiment Video

Updated: Dec 25, 2025

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery
10:03

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Published on: November 5, 2019

7.6K

Unexpected pathogen presenting with purulent meningitis.

Jamie Bering1, Carlos Hartmann2, Kara Asbury2

  • 1Department of Internal Medicine, Mayo Clinic, Phoenix, Arizona, USA.

BMJ Case Reports
|March 21, 2020
PubMed
Summary
This summary is machine-generated.

A man with chronic lymphocytic leukaemia developed Capnocytophaga canimorsus meningitis while on ibrutinib therapy. Prompt diagnosis and treatment led to a positive outcome, highlighting a rare but serious infection risk.

Keywords:
haematology (drugs and medicines)haematology (incl blood transfusion)infectionsmeningitistyrosine Kinase Inhibitor

More Related Videos

Humanized Mouse Model to Study Bacterial Infections Targeting the Microvasculature
11:40

Humanized Mouse Model to Study Bacterial Infections Targeting the Microvasculature

Published on: April 1, 2014

15.3K
Neisseria meningitidis Infection of Induced Pluripotent Stem-Cell Derived Brain Endothelial Cells
10:12

Neisseria meningitidis Infection of Induced Pluripotent Stem-Cell Derived Brain Endothelial Cells

Published on: July 14, 2020

2.7K

Related Experiment Videos

Last Updated: Dec 25, 2025

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery
10:03

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Published on: November 5, 2019

7.6K
Humanized Mouse Model to Study Bacterial Infections Targeting the Microvasculature
11:40

Humanized Mouse Model to Study Bacterial Infections Targeting the Microvasculature

Published on: April 1, 2014

15.3K
Neisseria meningitidis Infection of Induced Pluripotent Stem-Cell Derived Brain Endothelial Cells
10:12

Neisseria meningitidis Infection of Induced Pluripotent Stem-Cell Derived Brain Endothelial Cells

Published on: July 14, 2020

2.7K

Area of Science:

  • Infectious Diseases
  • Oncology
  • Neurology

Background:

  • Chronic lymphocytic leukaemia (CLL) is a common hematologic malignancy.
  • Ibrutinib is a targeted therapy used for CLL and other B-cell malignancies.
  • Patients on targeted therapies may be at increased risk for opportunistic infections.

Observation:

  • A 67-year-old man with CLL on ibrutinib presented with acute fever and altered mental status.
  • Cerebrospinal fluid analysis revealed Capnocytophaga canimorsus meningitis.
  • The patient's symptoms developed during ibrutinib treatment.

Findings:

  • This is the first reported case of invasive Capnocytophaga canimorsus meningitis in a patient receiving ibrutinib.
  • Capnocytophaga canimorsus is a bacterium typically associated with dog or cat bites.
  • Timely diagnosis and appropriate antimicrobial therapy resulted in a favorable outcome.

Implications:

  • Ibrutinib therapy may increase the risk of invasive Capnocytophaga canimorsus infections.
  • Clinicians should consider Capnocytophaga species in the differential diagnosis of meningitis in immunocompromised patients, especially those on ibrutinib.
  • Early recognition and treatment are crucial for managing these serious infections.