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Updated: Dec 25, 2025

Live-3D-Cell Immunocytochemistry Assays of Pediatric Diffuse Midline Glioma

Live-3D-Cell Immunocytochemistry Assays of Pediatric Diffuse Midline Glioma

Published on: November 11, 2021

H3K27M mutant diffuse midline glioma: a case report.

Y Luo¹, L Zeng, X-Q Xie

¹Department of Medical Oncology, Cancer Center, West China Hospital, West China Medical School, Sichuan University, Sichuan, P.R. China. wangfeng5024@126.com.

European Review for Medical and Pharmacological Sciences

|March 21, 2020

Summary

Diffuse midline glioma with H3K27M mutation, a challenging WHO CNS tumor, often presents in the brain midline with poor prognosis. This case highlights potential therapeutic avenues beyond traditional treatments.

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Area of Science:

Neuro-oncology
Molecular Pathology
Central Nervous System (CNS) Tumors

Background:

Diffuse midline glioma with H3K27M mutation is a newly classified WHO CNS tumor.
This tumor type typically affects midline brain structures and is associated with a poor prognosis.

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