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Updated: Dec 25, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
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Atrial fibrillation for internists: current practice.

Pascal Meyre1, David Conen2, Stefan Osswald1

  • 1Division of Cardiology, Department of Medicine, University Hospital Basel, Switzerland / Cardiovascular Research Institute Basel, University Hospital Basel, Switzerland.

Swiss Medical Weekly
|March 23, 2020
PubMed
Summary
This summary is machine-generated.

Atrial fibrillation (AF), a global epidemic, is linked to hypertension and obesity. Effective stroke prevention with oral anticoagulants and symptom management through rate/rhythm control are key, with ablation offering rhythm control options.

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Area of Science:

  • Cardiology
  • Internal Medicine
  • Epidemiology

Background:

  • Atrial fibrillation (AF) is a widespread condition associated with significant patient risk.
  • Understanding AF's risk factors, complications, and management is crucial for public health.

Purpose of the Study:

  • To review current evidence on atrial fibrillation (AF) risk factors and complications.
  • To describe established and emerging treatment strategies for AF.
  • To highlight new research directions in AF management.

Main Methods:

  • Literature review of current evidence on AF.
  • Synthesis of data on risk factors, complications, and treatments.
  • Identification of emerging research areas in AF.

Main Results:

  • Hypertension and obesity are primary modifiable risk factors for AF.
  • Oral anticoagulation, particularly non-vitamin K antagonists, significantly reduces stroke risk.
  • Rate and rhythm control interventions, including AF ablation, are vital for symptom management.

Conclusions:

  • Managing AF requires addressing modifiable risk factors like hypertension and obesity.
  • Optimizing anticoagulation and rhythm/rate control strategies is essential for patient outcomes.
  • Further research into AF's link with silent brain lesions and cognitive dysfunction is needed for novel interventions.