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Arrhythmogenic left ventricular cardiomyopathy

Seyedeh Mojdeh Mirmomen1, Andrew Jay Bradley1, Andrew Ernest Arai1

  • 1National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

BJR Case Reports
|March 24, 2020
PubMed

Insights

Arrhythmogenic ventricular cardiomyopathy (AVC) is a genetic heart condition causing fibrofatty tissue in the heart muscle. Primarily affecting the right ventricle, AVC can rarely involve the left ventricle, posing diagnostic challenges.

Area of Science:

  • Cardiology
  • Genetics
  • Pathology

Background:

  • Arrhythmogenic ventricular cardiomyopathy (AVC) is an inherited myocardial disorder.
  • It involves fibrofatty infiltration of the heart muscle, leading to arrhythmias and sudden cardiac death.

Observation:

  • The classic form, arrhythmogenic right ventricular cardiomyopathy (ARVC), primarily affects the right ventricle.
  • Left ventricular involvement can occur in advanced ARVC cases.

Findings:

  • Predominantly left ventricular AVC is rare.
  • Diagnosis is challenging due to lack of specific criteria and potential cardiotoxicity.

Implications:

  • Understanding predominantly left ventricular AVC is crucial for accurate diagnosis and management.
  • Further research is needed to develop diagnostic criteria for this rare subtype.

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