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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Prenatal stress: Effects on fetal and child brain development

Alexandra Lautarescu1, Michael C Craig2, Vivette Glover3

  • 1Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom; Perinatal Imaging and Health, Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.

International Review of Neurobiology
|March 25, 2020
PubMed
Summary

Prenatal maternal stress impacts offspring brain development, increasing risks for emotional, behavioral, and cognitive issues. Biological mechanisms involve the HPA axis and altered brain structures like the amygdala.

Keywords:
BrainCortisolFetusMRIPrenatalPsychopathologyStress

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