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Updated: Dec 25, 2025

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Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
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Internationally lost COVID-19 cases.
Hien Lau1, Veria Khosrawipour2, Piotr Kocbach3
1Department of Surgery, University of California, Irvine, Orange, 92868 CA, USA.
Summary
Countries with lower Healthcare Access and Quality (HAQ) Index scores may underreport or fail to detect COVID-19 cases. This reporting inconsistency poses a significant risk to global efforts to contain the pandemic.
Area of Science:
- Epidemiology
- Global Health
- Public Health Surveillance
Background:
- The COVID-19 pandemic, originating in Wuhan, China, prompted global health organizations to implement travel restrictions.
- Despite restrictions, international COVID-19 cases increased, raising concerns about undetected transmissions and potential new epicenters.
- The study addresses the critical need to understand international COVID-19 case reporting dynamics.
Purpose of the Study:
- To analyze international COVID-19 case data from January 20th to February 18th, 2020.
- To investigate the relationship between COVID-19 case reporting and national Healthcare Access and Quality (HAQ) Index scores.
- To identify potential disparities in COVID-19 detection and reporting across countries with varying healthcare standards.
Main Methods:
- Analysis of international COVID-19 case data (January 20 - February 18, 2020).
- Categorization of cases based on travel history to China and country HAQ-Index.
- Application of Chi-square and Post-hoc tests for statistical analysis.
Main Results:
- COVID-19 cases with travel history showed a peak in each HAQ-Index cohort.
- Non-travel related COVID-19 cases continuously increased in countries with higher HAQ-Index scores.
- Countries with lower HAQ-Index scores reported a significantly lower proportion of non-travel related COVID-19 cases (p < 0.01).
Conclusions:
- Lower HAQ-Index countries may underreport or inadequately detect COVID-19 cases.
- Discrepancies in COVID-19 case reporting present a substantial challenge to pandemic containment efforts.
- The findings underscore the importance of robust global surveillance and reporting systems for infectious diseases.
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