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Published on: January 17, 2018
Surgical approach to patients with hypercortisolism.
Colleen M Kiernan1, Carmen C Solórzano1
1Vanderbilt University Medical Center, Nashville, TN, USA.
This chapter reviews surgical management for Cushing's syndrome, focusing on controlling cortisol and its effects. It covers ACTH-dependent and independent hypercortisolism, including perioperative factors and robotic adrenalectomy.
Area of Science:
- Endocrinology
- Surgical Management
- Clinical Practice Guidelines
Background:
- Cushing's syndrome is characterized by hypercortisolism, leading to end-organ effects and comorbidities.
- Effective management aims to control cortisol levels or receptor activity.
Purpose of the Study:
- To review the surgical management of hypercortisolism.
- To discuss perioperative factors in surgical treatment.
- To evaluate robotic adrenalectomy for Cushing's syndrome.
Main Methods:
- Review of surgical strategies for ACTH-dependent hypercortisolism.
- Review of surgical strategies for ACTH-independent (adrenal) hypercortisolism.
- Discussion of perioperative considerations.
- Analysis of robotic adrenalectomy outcomes.
Main Results:
- Surgical management is a key treatment modality for Cushing's syndrome.
- Perioperative factors significantly influence surgical outcomes.
- Robotic adrenalectomy offers potential benefits and risks.
Conclusions:
- Surgical intervention is crucial for managing Cushing's syndrome.
- Careful consideration of perioperative factors is essential for successful surgical outcomes.
- Robotic adrenalectomy presents a viable, though complex, surgical option.
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