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Stereolithography 3D Bioprinting.

Hitendra Kumar¹, Keekyoung Kim^2,3

¹School of Engineering, University of British Columbia, Kelowna, BC, Canada.

Methods in Molecular Biology (Clifton, N.J.)

|March 25, 2020

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Stereolithography (SLA) 3D bioprinting advances tissue engineering with novel photocrosslinkable biomaterials and UV/visible light systems. This versatile technology shows promise for bone, neural tissue, and cellular microenvironment development with clinical applications.

Area of Science:

Biomaterials Science
Tissue Engineering
3D Bioprinting Technologies

Background:

Stereolithography (SLA) 3D bioprinting is a key technology for fabricating complex tissues.
Advancements in SLA are driven by the development of new photocrosslinkable biomaterials.
Novel biomaterials offer improved physical and chemical properties for tissue engineering.

Purpose of the Study:

To review advancements in SLA 3D bioprinting.
To discuss the role of novel photocrosslinkable biomaterials.
To explore applications in tissue engineering and cell behavior studies.

Main Methods:

Utilizing cytocompatible photoinitiators across UV and visible light spectra.
Employing high-resolution dynamic mask projection systems with suitable illumination.

Keywords:

Hydrogel scaffolds Photocrosslinking Stereolithography 3D bioprinting Tissue and organ regeneration

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Investigating applications in bone and neural tissue engineering.

Main Results:

SLA bioprinting enables the creation of complex tissue structures.
Photocrosslinkable biomaterials enhance fabrication capabilities.
Exploration of controlled microenvironments for cell behavior studies.

Conclusions:

SLA 3D bioprinting is a versatile and promising technology.
The integration of advanced biomaterials and light systems expands its potential.
Significant possibilities exist for clinical applications in regenerative medicine.