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Updated: Dec 25, 2025

Proteome-wide Quantification of Labeling Homogeneity at the Single Molecule Level
Published on: April 19, 2019
Drug Distribution in Living Cells via Label-Free Molecular Fingerprint
1Center for Protein Diagnostics, Ruhr University Bochum, Gesundheitscampus 4, 44801 Bochum, Germany.
Abstract:
A new application of stimulated Raman scattering (SRS) uses the benefit of a label-free molecular fingerprint to image the uptake and distribution of an alkyne-based drug in living cells. This method delivers information on cellular molecular composition and drug-cell interaction, showing the potential of SRS in drug development.
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