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Amino-containing tannic acid derivative-mediated universal coatings for multifunctional surface modification
Yan Fang Cheng1, Dicky Pranantyo2, Gopinath Kasi1
1Chongqing Key Laboratory for Advanced Materials and Technologies of Clean Energies, School of Materials and Energy, Southwest University, Chongqing, 400715, P.R. China. xulq@swu.edu.cn zslu@swu.edu.cn.
Biomaterials Science
|March 27, 2020
Summary
A new tannic acid derivative (TAA) forms universal, colorless coatings under mild conditions. This versatile surface modification strategy prevents protein adsorption and bacterial adhesion, enabling broad applications in materials science.
Area of Science:
- Materials Science
- Surface Chemistry
- Biomaterials
Background:
- Developing universal coating strategies for functional surfaces is crucial.
- Tannic acid (TA) can form colorless coatings but requires high salt concentrations.
- Limitations in TA deposition hinder practical applications.
Purpose of the Study:
- To develop an amine-containing tannic acid derivative (TAA) for mild-condition coating.
- To create a versatile, material-independent coating strategy.
- To demonstrate TAA's utility in surface functionalization and antimicrobial applications.
Main Methods:
- Introducing primary amine moieties onto tannic acid gallic acid groups.
- Self-polymerization of TAA under mild conditions (10 mM Tris buffer).
- Characterization of TAA coatings using ellipsometry and secondary functionalization.
Main Results:
- TAA forms uniform, colorless, and thicker coatings compared to TA.
- TAA coatings facilitate grafting of mPEG brushes to inhibit protein adsorption.
- TAA coatings enable immobilization of biotin probes for specific binding.
- AgNP-loaded TAA coatings effectively inhibit bacterial adhesion and biofilm formation.
Conclusions:
- TAA offers a universal, mild-condition coating strategy for diverse materials.
- TAA coatings provide a versatile platform for advanced surface functionalization.
- TAA-based coatings demonstrate significant potential for biomedical and antimicrobial applications.
