Synthesis of orthogonally reactive multilayered microcapsules

In this communication, a single polymer derived multilayered microcapsule loaded with orthogonally reactive residual functional groups-acrylate and amine-is synthesized by rational association of a facile layer-by-layer (LbL) deposition process and a catalyst-free 1,4-conjugate addition reaction under ambient conditions. This approach is appropriate for controlled chemical modulations of multilayered microcapsules with various electrophiles and nucleophiles following two independent reaction pathways.