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Related Concept Videos

Urinary Tract Infection II: Pathophysiology01:25

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The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
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Infection01:20

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Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Updated: Dec 25, 2025

Human Placental and Decidual Organ Cultures to Study Infections at the Maternal-fetal Interface
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[Systemic infections in obstetrics].

I Mylonas1, A Gingelmaier2, K Friese2

  • 12Frauenklinik, Ludwig-Maximilians-Universität, Maistraße 11, 80337 München, Deutschland.

Der Gynakologe
|March 28, 2020
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Summary
This summary is machine-generated.

Systemic infections during pregnancy are often missed due to mild or absent symptoms. Early serological TORCH testing is crucial for timely diagnosis and preventing severe long-term consequences for children.

Keywords:
InfectionObstetricsPregnancyTORCH

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Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Maternal-Fetal Medicine

Context:

  • Systemic infections in pregnancy are frequently underestimated.
  • Pregnant women often present with nonspecific, flu-like symptoms or remain asymptomatic.
  • Current German maternity care screening may fail to detect infections promptly.

Purpose:

  • To highlight the underappreciated significance of systemic infections during pregnancy.
  • To emphasize the diagnostic limitations of standard prenatal screening for infections.
  • To advocate for timely serological TORCH analysis in symptomatic pregnant women.

Summary:

  • Many pregnancy-related infections are asymptomatic or present with vague symptoms, leading to delayed diagnosis.
  • Serological screening in German maternity care is often insufficient for early detection of infections.
  • TORCH (Toxoplasmosis, Other, Rubella, Cytomegalovirus, Herpes) testing is recommended for pregnant women with suspicious symptoms.

Impact:

  • Timely diagnosis and treatment of infections can mitigate severe long-term health consequences for affected children.
  • Improved diagnostic strategies are needed to address the underestimation of infectious risks in pregnancy.
  • Early intervention can significantly improve outcomes for both the child and the family.