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Updated: Dec 25, 2025

Capillary Electrophoresis-based Hydrogen/Deuterium Exchange for Conformational Characterization of Proteins with Top-down Mass Spectrometry
Published on: June 8, 2021
Serum protein electrophoretic profile in diarrheic neonatal calves
Labrini V Athanasiou1, Panagiotis Dimitrios Katsoulos2, Christos Ziogas1
11Department of Medicine, Faculty of Veterinary Medicine, School of Health Sciences, University of Thessaly, GR-43100 Karditsa, Greece.
Abstract:
The electrophoretic profile of clinically healthy newborn calves and calves with neonatal diarrhea was compared. Blood samples were collected at 3 and 10 days of age from 11 calves that remained clinically healthy throughout the study period and 14 calves with diarrhea. A significant reduction in the gamma globulins was observed in the diarrheic calves that can be attributed to the transfer of serum immunoglobulins, to the intestinal lumen to counteract the infection. Moreover, a significant increase in the albumin was observed in this group between the sampling days that is mainly attributed to the relative reduction of the gamma globulin fraction.
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