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Lung Volume Reduction Surgery in Patients with Heterogenous Emphysema: Selecting Perspective
Nguyen Truong Giang1, Trung Nguyen Ngoc1, Nguyen Van Nam1
1Department of Cardiothoracic Surgery, Vietnam Military Medical University, Hanoi, Vietnam.
Open Access Macedonian Journal of Medical Sciences
|March 28, 2020
Summary
Identifying the best candidates for lung volume reduction surgery (LVRS) is crucial. Patients with severe heterogeneous emphysema and specific lung function test results (FEV1 ≤ 50%, TLC 100-140%) showed improved outcomes after LVRS.
Area of Science:
- Pulmonary Medicine
- Thoracic Surgery
- Respiratory Physiology
Background:
- Lung volume reduction surgery (LVRS) aims to improve clinical conditions in selected patients with heterogeneous emphysema.
- Optimal patient selection for LVRS remains a critical challenge.
Purpose of the Study:
- To identify preoperative factors that predict successful outcomes following LVRS.
- To refine patient selection criteria for LVRS in severe heterogeneous emphysema.
Main Methods:
- A prospective study involving 31 severe heterogeneous emphysema patients undergoing LVRS.
- Preoperative spirometry and body plethysmographic pulmonary function tests were analyzed.
- Postoperative outcomes, including changes in FEV1 and CAT scores, were compared with preoperative data.
Main Results:
- Patients with FEV1 ≤ 50% demonstrated significantly better improvements in FEV1 (22.46%) and CAT scores (6.85) compared to those with FEV1 > 50%.
- Total lung capacity (TLC) < 140% was associated with greater FEV1 improvement (23.81%).
- No significant differences in outcomes were observed based on residual volume groups.
Conclusions:
- Preoperative spirometry and body plethysmographic tests are valuable for selecting severe heterogeneous emphysema patients for LVRS.
- Recommended patient profile for LVRS includes FEV1 ≤ 50% and TLC in the range of 100-140%.
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