Related Experiment Video
Updated: Dec 25, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
Acute spontaneous suppurative thyroiditis caused by Eikenella corrodens presented with thyrotoxicosis
Pınar Akhanlı1, Ömer Bayır1, Seyit Murat Bayram1
1University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.
Acute suppurative thyroiditis, a rare endocrine emergency, can spontaneously cause thyrotoxicosis. This case highlights a patient with spontaneous acute suppurative thyroiditis presenting with thyrotoxic findings.
Area of Science:
- Endocrinology
- Infectious Diseases
Background:
- Acute suppurative thyroiditis is a rare endocrine emergency.
- Thyrotoxicosis is an uncommon complication of acute suppurative thyroiditis.
- Spontaneous development of acute suppurative thyroiditis is exceptionally rare.
Observation:
- A 31-year-old male presented with neck pain, swelling, redness, fever, and palpitations.
- Physical examination revealed thyroid-region swelling, tenderness, tremor, tachycardia, and agitation.
- Biochemical tests indicated thyrotoxicosis and infection; radiological evaluation showed a heterogeneous left thyroid lesion.
Findings:
- Fine needle aspiration yielded purulent fluid.
- Eikenella corrodens was identified in culture.
- The patient received antibiotics, propranolol, steroids, and symptomatic treatment, recovering fully.
Implications:
- Acute suppurative thyroiditis can occur spontaneously with thyrotoxicosis, even without risk factors.
- This case underscores the importance of considering spontaneous acute suppurative thyroiditis in patients with thyrotoxic symptoms.
- Prompt diagnosis and treatment are crucial for managing this life-threatening condition.
Related Concept Videos
Synthesis and Regulation of Thyroid Hormones
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Endocarditis II: Clinical Features of Infective Endocarditis
Myocarditis II: Clinical Features and Diagnostic Tests
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Acute Coronary Syndrome I: Introduction

