CdS quantum dots embedded in PVP: Inorganic phosphate ion sensing in real sample and its antimicrobial activity

Polyvinyl-pyrrolidone capped spherical cadmium sulphide quantum dots (CdS-PVP QDs), 2-6 nm in size, were developed as a selective turn-on fluorescence nanosensor for monohydrogen phosphate ion (HPO₄^2-) in aqueous medium. Fluorescence intensity of CdS-PVP QDs significantly increased with addition of HPO₄^2- ions, whereas the other common inorganic ions had very little effect on the fluorescence intensity. The proposed sensor may be efficiently used for the detection of HPO₄^2- ions at a low level of concentration up to 213 nM in real urine sample. Cell imaging study indicates that the CdS-PVP QDs are cell permeable and can detect the intracellular distribution of HPO₄^2- ions under fluorescence microscope. The CdS-PVP QDs showed considerable activity against Staphylococcus aureus also.