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Updated: Dec 25, 2025

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management
Published on: November 30, 2022
Allocation of scarce biospecimens for use in research
Leah Pierson1, Sophia Gibert2, Benjamin Berkman3
1MD-PhD Program, Harvard Medical School, Boston, Massachusetts, USA leah_pierson@hms.harvard.edu.
Abstract:
Hundreds of millions of rare biospecimens are stored in laboratories and biobanks around the world. Often, the researchers who possess these specimens do not plan to use them, while other researchers limit the scope of their work because they cannot acquire biospecimens that meet their needs. This situation raises an important and underexplored question: how should scientists allocate biospecimens that they do not intend to use? We argue that allocators should aim to maximise the social value of the research enterprise when allocating scarce biospecimens. We provide an ethical framework for assessing the social value of proposed research projects and describe how the framework could be implemented.

