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Updated: Dec 25, 2025

Author Spotlight: Isolation and Culture of Primary Synovial Macrophages and Fibroblasts from Murine Arthritis Tissue
Published on: February 24, 2023
Synovial Myxoma: Found in Canines, Rabbits, and Now Humans Too?: A Case Report
Alana M Munger1, Izuchukwu K Ibe1, Douglas Rottmann2
1Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, Connecticut.
Case:
A 63 year-old woman presented with a multiple-year history of right knee pain and effusions and pain refractory to numerous knee aspirations and an arthroscopic synovectomy. The patient underwent a 2-incision synovectomy and intralesional resection. A pathologic review of the specimens revealed an infiltrative tumor of basophilic, cluster of differentiation 68-positive synovial cells embedded within a myxoid stroma with low proliferative activity, most consistent with a synovial myxoma.
Conclusions:
This case report of a synovial myxoma-a benign, slow growing but locally aggressive mass that is most commonly found in canines-indicates that the lesion may occasionally occur in humans.
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