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Related Concept Videos

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

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Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
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Related Experiment Video

Updated: Dec 25, 2025

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
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A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

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Neonatal Sepsis.

Muhammed Ershad1, Ahmed Mostafa1, Maricel Dela Cruz1

  • 1College of Medicine, Drexel University, 245 N 15th St, MS #1011, Philadelphia, PA 19102 USA.

Current Emergency and Hospital Medicine Reports
|April 1, 2020
PubMed
Summary
This summary is machine-generated.

Neonatal sepsis, a serious infection in infants under 28 days, requires prompt recognition and antibiotic treatment. Early diagnosis is crucial for managing this potentially life-threatening condition in newborns.

Keywords:
neonatal feverneonatal sepsisnewborn fevernewborn sepsis

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Last Updated: Dec 25, 2025

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Area of Science:

  • Neonatology
  • Infectious Diseases
  • Pediatrics

Background:

  • Neonatal sepsis is a clinical syndrome in infants less than 28 days old.
  • It can manifest with systemic signs of infection, shock, and organ failure.
  • Delayed recognition increases the risk of severe outcomes.

Purpose of the Study:

  • To review the key aspects of neonatal sepsis.
  • To highlight common pathogens and risk factors.
  • To emphasize the importance of timely diagnosis and treatment.

Main Methods:

  • Review of current literature on neonatal sepsis.
  • Identification of common bacterial pathogens (e.g., Staphylococcus aureus, Escherichia coli).
  • Analysis of risk factors such as central venous catheter use and prolonged hospitalization.

Main Results:

  • Staphylococcus aureus and Escherichia coli are frequently implicated bacteria.
  • Central venous catheter use and prolonged hospitalization are significant risk factors.
  • Blood culture is the gold standard for diagnosing neonatal sepsis.

Conclusions:

  • Neonatal sepsis necessitates a high index of suspicion.
  • Immediate antibiotic administration is critical for effective management.
  • Prompt intervention improves outcomes for affected neonates.