[The human lectin supersystems possessing probiotic and protective actions.]

Area of Science:

• Biotechnology
• Immunology
• Carbohydrate Chemistry

Background:

• Lectins are proteins that recognize carbohydrates.
• Human immunobiological supersystems of lectins (SSL) are described, focusing on their interaction with carbohydrates and glycoconjugates.
• These interactions occur within molecular or supramolecular protein/(oligo)peptide-containing constituents of biotopes.

Purpose of the Study:

• To describe the potential of human immunobiological supersystems of lectins (SSL).
• To highlight the key features and applications of SSL in recognizing and binding carbohydrates.
• To evaluate the prospects of SSL in diagnostics, therapy, and medical biotechnology.

Main Methods:

• Describing the recognition and reversible binding capabilities of SSL.
• Detailing the delivery and orientation of glycoconjugates at the cell surface by SSL.
• Evaluating the application of SSL in probiotics, complement C4 system, and protein hormones like erythropoietins.

Main Results:

• SSL can recognize, reversibly bind, and orient natural or synthetic glycoconjugates at the cell surface.
• Key features of SSL relevant to their function are identified.
• Potential applications in diagnostics, prophylaxis, and therapy of diseases are outlined.

Conclusions:

• SSL possess significant potential for human immunobiological applications.
• Their ability to interact with carbohydrates makes them valuable tools in medical biotechnology.
• SSL show promise in the prognostics, diagnostics, prophylaxis, and therapy of various pathologies.