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Updated: Dec 25, 2025

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
Coronary dissection with ST elevation myocardial infarction responding to thrombolytic and conservative therapy alone
Morteza Safi1, AliReza Serati2, Sepideh Emami3
1Cardiovascular Research Center, Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Insights
Spontaneous coronary artery dissection, a rare cause of heart attack, may heal on its own. This case highlights successful conservative treatment for spontaneous coronary dissection, suggesting it
Area of Science:
- Cardiology
- Vascular Medicine
Background:
- Spontaneous coronary artery dissection (SCAD) is a rare cause of myocardial infarction.
- Management strategies for SCAD, particularly conservative versus invasive approaches, are debated.
Observation:
- A case of SCAD involving the left anterior descending artery presented as acute anterior myocardial infarction.
- The patient refused an initial angiogram, making pre-intervention assessment challenging.
Findings:
- Successful treatment with thrombolytic and conservative therapy was achieved.
- The findings suggest spontaneous thrombus resolution may have occurred before intervention was considered.
- This case implies that SCAD may heal spontaneously and can be managed conservatively in select patients.
Implications:
- Conservative management for SCAD is a viable option in carefully selected cases.
- Individualized treatment decisions are crucial, considering clinical judgment and patient stability.
- Coronary interventions should be reserved for cases unresponsive to conservative therapy or with hemodynamic compromise.
Abstract:
In this report, we describe a case of spontaneous coronary dissection involving left anterior descending artery presenting with acute anterior myocardial infarction successfully treated with thrombolytic and conservative therapy with a suggestion that spontaneous resolution of thrombus occurred before coronary intervention could be performed. As we did not have initial angiogram due to patient's refusal, this assumption is speculative. However, this case suggests that dissections may heal spontaneously and could be treated with conservative approach in selected cases based on best clinical judgment. It is important to realize that the clinical course of a major coronary artery dissection remains unpredictable. Therefore, cardiologists should always treat each case individually and consider coronary interventions if conservative treatment is not leading to resolution of ST elevation or in patients with hemodynamic compromise. This case is followed by discussion about conservative versus invasive management of spontaneous coronary dissections.
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