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Related Concept Videos

Brain Imaging01:14

Brain Imaging

588
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
588

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Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure
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Pediatric Functional Neuroimaging: Practical Tips and Pearls.

Jeremy Y Jones1, Bhavani Selvaraj1, Mai-Lan Ho1

  • 1Department of Radiology, Nationwide Children's Hospital, 700 Children's Dr, ED4, Columbus, OH 43205.

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|April 2, 2020
PubMed
Summary
This summary is machine-generated.

Pediatric functional MRI (fMRI) aids in localizing brain function before surgery. Special considerations for children include preparation, study design, and interpretation due to developmental differences.

Keywords:
blood oxygenation level–dependent (BOLD) imagingfunctional MRI (fMRI)paradigmpediatric

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Area of Science:

  • Neuroimaging
  • Pediatric Radiology

Background:

  • Functional MRI (fMRI) is crucial for pre-surgical mapping of eloquent cortex, particularly motor and language areas.
  • Pediatric fMRI presents unique challenges including patient tolerance, anatomical differences, and developmental variations.

Purpose of the Study:

  • To outline key considerations, potential challenges, and best practices for clinical pediatric fMRI.
  • To provide guidance on fMRI principles, patient preparation, acquisition, processing, and interpretation in children.

Main Methods:

  • Review of principles of blood oxygenation level-dependent (BOLD) imaging.
  • Discussion of pediatric-specific patient preparation and study design strategies.
  • Overview of data postprocessing and interpretation nuances for pediatric fMRI.

Main Results:

  • Successful pediatric fMRI requires tailored approaches to overcome challenges related to age and development.
  • Understanding developmental neuroanatomy and neuroplasticity is vital for accurate interpretation.

Conclusions:

  • Clinical fMRI is essential for pre-surgical localization in pediatric patients with neurological conditions.
  • Radiologists must be aware of pediatric-specific factors for effective fMRI application and interpretation.