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A new recombinant F1 antigen as a cost and time-effective tool for plague diagnosis
Diego H C Tavares1, Matheus F Bezerra2, Franklin B Magalhães3
1Departamento de Microbiologia - Instituto Aggeu Magalhães, Fiocruz, Recife, Pernambuco, Brazil; Centro Universitário Vale do Ipojuca - Unifavip/Wyden, Caruaru, Pernambuco, Brazil.
Journal of Microbiological Methods
|April 2, 2020
Abstract:
The Yersinia pestis capsular antigen F1 is widely used in plague laboratory diagnosis. Here, we describe the production of an F1 recombinant protein within reduced time and biosafety requirements. Its evaluation in hemagglutination tests indicated that the recombinant F1 can replace the conventional F1 protein for plague diagnosis.

