Hyporeninemic hypoaldosteronism after renal transplantation

Hyperkalemic hyperchloremic metabolic acidosis developed in a patient with posttransplantation renal insufficiency presumably related to allograft rejection. The diagnosis of hyporeninemic hypoaldosteronism was confirmed by finding normal plasma cortisol levels and inappropriately low plasma renin activity and plasma aldosterone concentration in response to stimulating maneuvers.