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Updated: Dec 25, 2025

Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
Stereotactic Body Radiotherapy Using CyberKnife® for Localized Low- and Intermediate-risk Prostate Cancer: Initial
Ryosuke Nakamura1, Takero Hirata2, Osamu Suzuki1
1Department of Radiation Oncology, Osaka University Graduate School of Medicine, Osaka, Japan.
Background:
The present study aimed to evaluate the toxicity and efficacy of stereotactic body radiotherapy (SBRT) for localized prostate cancer.
Patients And Methods:
We investigated 25 patients treated with SBRT of 35 Gy per five fractions from May 2014 to March 2015.
Results:
The median age of patients was 70 years, four (16%) patients were low risk and 21 (84%) were intermediate risk. Seven (28%) patients received neoadjuvant androgen-deprivation therapy. The median follow-up time was 53 months. Grade 2 acute and late genitourinary toxicities were observed in five (20%) and two (8%) patients and there were no Grade 2 gastrointestinal toxicities. There were no Grade 3 or higher acute or late toxicities at 2 years follow-up. The biochemical relapse-free survival rate at 2 years was 100%.
Conclusion:
SBRT of 35 Gy per five fractions is a promising treatment method in the short term for prostate cancer.

