Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Invasive Infection Caused by a Hypervirulent ST367-KL1 Klebsiella quasipneumoniae subsp. similipneumoniae: First Case Report in Japan.

Japanese journal of infectious diseases·2026

Same author

Floatony formation in liquid environments: liquid drawing-based fabrication of three-dimensional microbial structures.

Biofabrication·2026

Same author

Detection of skatole using a phage display-derived peptide-modified graphene FET.

Talanta·2026

Same author

Inflammation-induced cell-secreted migrasome promotes IL-6 expression in the recipient cells.

Biomaterials advances·2026

Same author

Thoracic Aortic Aneurysm Following Blunt Trauma in a Patient with a Monoallelic <i>SLC2A10</i> Variant: A Case Report.

Annals of vascular diseases·2026

Same author

Ligand-modified liposomes as drug delivery systems for the active targeting of pancreatic cancer.

International journal of pharmaceutics: X·2026

Search research articles

Related Experiment Video

Updated: Dec 25, 2025

A Rapid and Quantitative Fluorimetric Method for Protein-Targeting Small Molecule Drug Screening

A Rapid and Quantitative Fluorimetric Method for Protein-Targeting Small Molecule Drug Screening

Published on: October 16, 2015

Array-Based Screening of Silver Nanoparticle Mineralization Peptides.

Masayoshi Tanaka¹, Shogo Saito¹, Reo Kita²

¹Department of Chemical Science and Engineering, Tokyo Institute of Technology, 2-12-1, O-okayama, Meguro-ku, Tokyo 152-8552, Japan.

International Journal of Molecular Sciences

|April 3, 2020

Summary

This summary is machine-generated.

Researchers screened peptides for silver nanoparticle (AgNP) synthesis. Specific peptide sequences, particularly those with EE or E[X]E motifs, enhance AgNP mineralization, enabling controlled synthesis of nanoparticles.

Keywords:

AgNP biomineralization green synthesis peptide array

More Related Videos

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

Published on: July 26, 2017

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery

Published on: May 16, 2021

Related Experiment Videos

Last Updated: Dec 25, 2025

A Rapid and Quantitative Fluorimetric Method for Protein-Targeting Small Molecule Drug Screening

A Rapid and Quantitative Fluorimetric Method for Protein-Targeting Small Molecule Drug Screening

Published on: October 16, 2015

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

Published on: July 26, 2017

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery

Published on: May 16, 2021

Area of Science:

Biomaterials Science
Nanotechnology
Peptide Chemistry

Background:

Biomolecules are increasingly used for nanomaterial synthesis under ambient conditions.
Short peptides can act as ligands for metallic surfaces, controlling nanoscale material synthesis.
Peptide-mediated silver nanoparticle (AgNP) synthesis requires further investigation for property control.

Purpose of the Study:

To evaluate the AgNP mineralization activity of 200 spot synthesis-based peptides.
To identify peptide sequences that effectively mediate AgNP synthesis.
To explore the potential of peptide-regulated AgNP mineralization for controlled nanoparticle morphology.

Main Methods:

Utilized an array of 200 synthesized peptides, previously identified for gold nanoparticle (AuNP) interactions.
Screened peptides for their ability to induce and control AgNP mineralization.
Analyzed the amino acid sequences of high-performing peptides for common motifs.

Main Results:

Identified 10 peptides (TOP10) with high AgNP synthesis activity.
Found that nine of the TOP10 peptides contained EE or E[X]E motifs (E: glutamic acid).
Observed that the size and morphology of AgNPs synthesized by the top three peptides were sequence-dependent.

Conclusions:

Array-based screening is effective for identifying peptides that mediate AgNP mineralization.
The presence of specific motifs, like EE and E[X]E, is crucial for efficient AgNP synthesis.
Peptide-regulated AgNP mineralization offers a pathway for environmentally friendly synthesis of AgNPs with controlled characteristics.