Jittering stimulus onset attenuates short-latency, synchronized-spontaneous otoacoustic emission energy

Synchronized-spontaneous otoacoustic emissions (SSOAEs) are slow-decaying otoacoustic emissions (OAEs) that persist up to several hundred milliseconds following presentation of a transient stimulus. If the inter-stimulus interval is sufficiently short, SSOAEs will contaminate the stimulus window of the adjacent epoch. In medial-olivocochlear reflex (MOCR) assays, SSOAE contamination can present as a change in the stimulus between quiet and noise conditions, since SSOAEs are sensitive to MOCR activation. Traditionally, a change in the stimulus between MOCR conditions implicates acoustic reflex activation by the contralateral noise; however, this interpretation is potentially confounded by SSOAEs. This study examined the utility of jittering stimulus onset to desynchronize and cancel short-latency SSOAE energy. Transient-evoked (TE) OAEs and SSOAEs were measured from 39 subjects in contralateral-quiet and -noise conditions. Clicks were presented at fixed and quasi-random intervals (by introducing up to 8 ms of jitter). For the fixed-interval condition, spectral differences in the stimulus window between quiet and noise conditions mirrored those in the SSOAE analysis window, consistent with SSOAE contamination. In contrast, spectral differences stemming from SSOAEs were attenuated and/or absent in the stimulus window for the jitter conditions. The use of jitter did not have a statistically significant effect on either TEOAE level or the estimated MOCR.