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Updated: Dec 25, 2025

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Generating iPS Cells from MEFS through Forced Expression of Sox-2, Oct-4, c-Myc, and Klf4
Published on: April 7, 2008
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Rudolf Virchow, the founder of cellular pathology
1Department of Basic Medical Sciences, Neurosciences and Sensory Organs, University of Bari Medical School, Bari, Italy; domenico.ribatti@uniba.it.
Abstract:
The cell theory was firstly formulated by Schleiden, Schwann, and Virchow. They sustained that the cells originate from pre-existing cells and that the living organisms are composed by cells organized in different tissues. In particular, Virchow not only established the principle of omnis cellula e cellula, but considered for the first time that alterations on cell organization was at the basis of disease.

