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Bacterial keratitis due to Moraxella nonliquefaciens
A Díaz Barrón1, L Sanz Gallen1, J M Hervás Hernandis1
1Departamento de Oftalmología, Hospital Clínico Universitario de Valencia, Valencia, España.
Moraxella nonliquefaciens keratitis is rare but serious, often affecting elderly patients with prior eye issues. Prompt, targeted antibiotic treatment guided by an antibiogram is crucial for successful outcomes.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Moraxella keratitis can lead to severe complications, with Moraxella nonliquefaciens (M. nonliquefaciens) presenting the worst prognosis.
- Published cases of corneal infections specifically due to M. nonliquefaciens are extremely rare, highlighting the need for increased awareness.
Observation:
- A case study details a 79-year-old male patient with bullous keratopathy who developed severe infectious keratitis.
- Clinical examination revealed dense, deep, central stromal infiltrates and hyphaema, indicative of a serious corneal infection.
Findings:
- M. nonliquefaciens was identified in corneal cultures.
- Treatment was adjusted to topical ciprofloxacin and ceftazidime, along with oral ciprofloxacin and amoxicillin-clavulanate, based on antibiogram results.
- Complete resolution of the keratitis lesion was achieved after 27 days, with a residual central leucoma.
Implications:
- M. nonliquefaciens keratitis should be suspected in elderly individuals with predisposing ocular factors like corneal damage or prior surgery.
- Early diagnosis, antibiogram-guided therapy, and close patient monitoring are essential to prevent complications and ensure treatment compliance.
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