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Comparison of Video, App, and Standard Consent Processes on Decision-Making for Biospecimen Research: A Randomized

Erin Rothwell1, Erin Johnson1, Bob Wong1

  • 1The University of Utah, Salt Lake City, USA.

Journal of Empirical Research on Human Research Ethics : JERHRE
|April 4, 2020
PubMed

Insights

New methods for obtaining informed consent for newborn bloodspot research, using video or interactive apps, improved participant understanding and satisfaction compared to traditional brochures.

Area of Science:

  • Bioethics
  • Informed Consent
  • Public Health Research

Background:

  • Informed consent for newborn bloodspot research is challenging due to the postnatal environment and the abstract nature of future research.
  • Current standard consent methods may not adequately inform parents.
  • Optimizing consent processes is crucial for ethical biospecimen research.

Purpose of the Study:

  • To compare the effectiveness of video and interactive tablet consent processes against standard brochure-based consent for newborn screening bloodspot research.
  • To evaluate participant knowledge, satisfaction, and clarity of information.
  • To inform best practices for obtaining informed consent in biospecimen research.

Main Methods:

  • A randomized controlled trial was conducted in three Michigan hospitals.
  • Compared two novel consent methods (video, interactive tablet app) with standard brochure consent.
  • Assessed outcomes including knowledge scores, satisfaction, and information clarity.

Main Results:

  • Video and interactive tablet consent groups demonstrated higher knowledge scores compared to the standard brochure group.
  • Participants in the video and app groups reported significantly higher satisfaction.
  • Both novel methods improved the perceived amount and clarity of information provided.

Conclusions:

  • Video and interactive tablet consent processes are more effective than standard brochures for newborn bloodspot research.
  • Further research is needed to determine optimal information levels for decision-making.
  • Feasibility studies are required to assess the implementation of these improved consent strategies.
Keywords:
biospecimensbloodspotsconsentmultimedianewborn screening

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