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Updated: Dec 25, 2025
A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
Orthodontic and Surgical Principles for Distraction Osteogenesis in Children with Pierre-Robin Sequence
Stephen Yen1, Austin Gaal2, Kevin S Smith3
1Division of Dentistry, Children's Hospital Los Angeles, 4650 Sunset Blvd, MS 116, Los Angeles, CA 90027, USA; Center for Craniofacial Molecular Biology, University of Southern California, CSA 103, 2250 Alcazar St. Los Angeles, CA 90033, USA.
Abstract:
Patients with Pierre-Robin sequence recalcitrant to nonsurgical intervention have historically required tracheostomy. Mandibular distraction provides a predictable alternative to tracheostomy. Orthodontic perioperative interventions should be considered, including overcorrection, placement of temporary anchorage devices, elastics, and molding the regenerate. Mandibular distraction can be technically difficult and may cause complications. Performed correctly, mandibular distraction provides patients with a better quality of life than tracheostomy.
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