Related Experiment Video
Updated: Dec 24, 2025

Isolation of Human Islets from Partially Pancreatectomized Patients
Published on: July 30, 2011
The impact of preoperative carbohydrate loading on patients with type II diabetes in an enhanced recovery after
Stephanie D Talutis1, Su Yeon Lee2, Daniel Cheng3
1Department of Surgery, Boston Medical Center, Boston, MA, USA.
Background:
We aimed to determine the effects of preoperative carbohydrate-loading (CHO) as part of an enhanced recovery after surgery (ERAS) pathway on patients with/without type II diabetes (DMII).
Methods:
Retrospective review of ERAS patients with CHO, including 80 with DMII, 275 without DMII in addition to 89 patients with DMII from the previous (non-ERAS) year. Outcomes included glucose-levels, insulin requirements, and complications. Logistic regression was used to determine the association of any complication with perioperative glucose control variables.
Results:
Among ERAS versus non-ERAS patients with DMII, there were significant differences in median preoperative (142 mg/dL versus 129.5 mg/dL, p = 0.017) and postoperative day-1 glucose levels (152 mg/dL, versus 137.5 mg/dL, p = 0.004). There were no differences in insulin requirements, hypoglycemic episodes, or complications. Complications were not associated with Hgb-A1C%, home DMII-medications, or preoperative glucose measurement on logistic regression.
Conclusions:
Patients with DMII tolerated CHO without increasing insulin requirements or substantially affecting glucose levels or complications.
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Peripheral Artery Disease V: Postoperative Nursing Management
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...

