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Updated: Dec 24, 2025

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Surface modification: activation and deactivation of osteogenic differentiation based on detachable growth factor
Zhen-Yu Guan1, Yi-Kai Chen, Chih-Yu Wu
1Department of Chemical Engineering, National Taiwan University, Taipei 10617, Taiwan. hsychen@ntu.edu.tw jiayu@ntu.edu.tw.
Journal of Materials Chemistry. B
|April 8, 2020
Abstract:
An advanced material interface is modified by using a substrate-independent coating of detachable poly-para-xylylene, enabling dynamical control of the immobilization and detachment of biomolecules, and a previously installed biological function is deactivated or tuned with reduced activity. The induction of osteogenesis activity, and subsequent deactivation of such osteogenesis activity, is demonstrated.

