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Updated: Dec 24, 2025
Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells
Published on: March 16, 2017
NIR fluorescent organic nanoparticles for photoinduced nitric oxide delivery with self monitoring and real time
Krishna Kalyani Behara1, Y Rajesh, Amrita Chaudhuri
1Department of Chemistry, Indian Institute of Technology (IIT) Kharagpur, Kharagpur-721302, India. ndpradeep@chem.iitkgp.ernet.in.
Abstract:
Nitric oxide photodonor (NOD) conjugated perylene tetracarboxylate ester (TPT) based fluorescent organic TPT(NOD)4 nanoparticles (NPs) with aggregation induced NIR emission have shown photoinduced nitric oxide delivery along with a red to green emission transition. Time dependent imaging and dose dependent cytotoxicity studies of these NPs using U87MG cells demonstrate the self monitoring and real time reporting abilities and potential anticancer activity of the system, respectively.
