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Microscopic Polyangiitis Initially Presumed to Be Endocarditis
Takahiro Kaneko1, Shunsuke Hino1, Yosuke Iijima1
1Department of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Abstract:
The antineutrophil cytoplasmic antibody- (ANCA-) associated vasculitides (AAVs), which include fever of unknown origin (FUO), are rare diseases characterized by necrotizing inflammation of small blood vessels and the presence of ANCAs. Microscopic polyangiitis (MPA) is a subtype of the AAVs. Although the prevalence of AAVs has generally increased over the last 20 years, there have been rare reports from the dental and oral surgery field. In this article, we present a case of MPA suspected to be infective endocarditis (IE) following tooth extraction.
Insights
Antineutrophil cytoplasmic antibody-associated vasculitides (AAVs), including microscopic polyangiitis (MPA), are rare small vessel diseases. This case highlights MPA mimicking infective endocarditis after a dental procedure.
Area of Science:
- Rheumatology
- Immunology
- Vascular Medicine
Background:
- Antineutrophil cytoplasmic antibody-associated vasculitides (AAVs) are rare systemic autoimmune diseases.
- Fever of unknown origin (FUO) can be a presenting symptom of AAVs.
- Microscopic polyangiitis (MPA) is a specific subtype of AAVs affecting small blood vessels.
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