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Updated: Dec 24, 2025

An All-in-one Sample Holder for Macromolecular X-ray Crystallography with Minimal Background Scattering
Published on: July 6, 2019
Development of a sample holder for synchrotron radiation-based computed tomography and diffraction analysis of
Masayuki Uesugi1, Kaori Hirahara2, Kentaro Uesugi1
1Japan Synchrotron Radiation Research Institute (JASRI/SPring-8), 1-1-1 Kouto, Sayo, Hyogo 679-5198, Japan.
Abstract:
A sample holder for a suite of synchrotron radiation measurements on extraterrestrial materials, which are fragile and irregularly shaped, was developed using carbon nanotubes and polyimide. The holder enables investigation of such samples with multiple analytical instruments, which means that we can reduce the number of sample transfers between holders. The holder developed in our study also enables investigation of such samples without exposure to the terrestrial atmosphere, which contains abundant contaminants, such as water vapor and organic substances. The stability of the samples in the holder during the measurements and disturbance of the analysis result by the holder were evaluated, which showed that sample drift motion and image disturbance due to x-ray attenuation and scattering of the holder materials are insignificant.
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