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Updated: Dec 24, 2025
Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
Published on: February 1, 2022
Probe-label-free electrochemical aptasensor based on methylene blue-anchored graphene oxide amplification
Jing Rong Chen1, Xiao Xia Jiao, Hong Qun Luo
1Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China. linb@swu.edu.cn luohq@swu.edu.cn.
Abstract:
Two novel probe-label-free electrochemical aptasensors based on methylene blue (MB)-anchored graphene oxide (GO) amplification were developed for thrombin (TB) and ATP detection, taking advantage of the specific binding affinity of the aptamer towards the target and the different affinities of GO for MB, ssDNA, dsDNA, and G-quadruplex.
