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Polymeric theranostics: using polymer-based systems for simultaneous imaging and therapy.

Theodora Krasia-Christoforou1, Theoni K Georgiou

  • 1Department of Mechanical and Manufacturing Engineering, University of Cyprus, P.O. Box 20537, 1678 Nicosia, Cyprus. krasia@ucy.ac.cy.

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|April 9, 2020
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Summary
This summary is machine-generated.

Polymeric nanomedicine is advancing, with new systems combining therapy and imaging for theranostics. This review covers drug delivery, gene delivery, photodynamic therapy, and hyperthermia, integrated with advanced imaging techniques.

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Nanotechnology

Background:

  • Polymer-based nanomedicine is a rapidly expanding field.
  • Polymeric systems are widely used for drug/gene delivery and bioimaging.
  • Combining therapy and imaging in polymeric systems (theranostics) is an emerging area.

Purpose of the Study:

  • To review recent developments and trends in polymeric theranostics.
  • To explore the combination of therapeutic applications with imaging modalities.
  • To highlight advancements in theranostic nanomedicine.

Main Methods:

  • Literature review of polymeric theranostic systems.
  • Analysis of therapeutic modalities including drug delivery, gene delivery, photodynamic therapy, and hyperthermia.
  • Examination of integrated imaging techniques such as MRI, fluorescence imaging, and ultrasound.

Main Results:

  • Polymeric systems are increasingly designed for combined therapeutic and diagnostic functions.
  • Theranostic platforms integrate diverse treatment strategies with various imaging modalities.
  • Significant progress has been made in developing multifunctional polymeric nanomedicines.

Conclusions:

  • Polymeric theranostics represent a significant advancement in nanomedicine.
  • The integration of therapy and imaging offers enhanced disease management and diagnosis.
  • Future research will likely focus on further optimizing these combined systems for clinical translation.