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Wholly printed polypyrrole nanoparticle-based biosensors on flexible substrate
Bo Weng1, Aoife Morrin, Roderick Shepherd
1Chongqing Key Lab for Advanced Materials & Clean Energies of Techonologies, Institute for Clean Energy and Advanced Materials, Southwest University, 2 Tiansheng Rd, Beibei, Chongqing, China 400715.
Journal of Materials Chemistry. B
|April 9, 2020
Summary
We developed a novel polypyrrole (PPy) biosensor using inkjet printing for rapid, low-cost fabrication. This PPy biosensor effectively detects hydrogen peroxide (H2O2) and glucose.
Area of Science:
- Materials Science
- Electrochemistry
- Biosensors
Background:
- Printing technologies offer scalable and cost-effective manufacturing for sensor applications.
- Conducting polymers like polypyrrole (PPy) are suitable for biosensor development due to their electrochemical properties.
Purpose of the Study:
- To fabricate a wholly-printed polypyrrole (PPy) based biosensor using inkjet printing.
- To incorporate enzymes for specific analyte detection and a permselective membrane for enhanced functionality.
- To characterize the performance of the PPy biosensor for hydrogen peroxide (H2O2) and glucose detection.
Main Methods:
- Inkjet printing of PPy nanoparticle dispersions with immobilized enzymes (horseradish peroxidase or glucose oxidase).
- Deposition of an ethyl cellulose (EC) permselective membrane via inkjet printing.
- Electrochemical characterization using cyclic voltammetry (CV) and chrono-amperometry.
Main Results:
- Successful fabrication of PPy-based biosensors using inkjet printing.
- Demonstrated detection of H2O2 in the range of 10 μM–10 mM.
- Demonstrated detection of glucose in the range of 1–5 mM.
Conclusions:
- Inkjet printing is a viable method for rapid and low-cost fabrication of PPy biosensors.
- The developed PPy biosensor exhibits promising performance for detecting H2O2 and glucose.
