Related Experiment Video
Updated: Dec 24, 2025
Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors
Published on: September 10, 2013
A multifunctional perylenediimide derivative (DTPDI) can be used as a recyclable specific Hg2+ ion sensor and an
Kelan Liu1, Zejun Xu, Meizhen Yin
1State Key Laboratory of Chemical Resource Engineering, Key Laboratory of Carbon Fiber and Functional Polymers, Ministry of Education, Beijing University of Chemical Technology, 100029 Beijing, China. yinmz@mail.buct.edu.cn.
Abstract:
Multifunctional dithioacetal-modified perylenediimide (DTPDI) is synthesized as a highly sensitive and selective fluorescent chemosensor for recyclable Hg2+ detection and an effective DNA carrier. The central PDI chromophore allows the tracing of cell uptake by fluorescence microscopy, dithioacetals enable the detection of Hg2+, and peripheral amine hydrochloride salts increase the water solubility and also serve as positive charges for noncovalent binding of negatively charged DNA. In addition to serve as a recyclable fluorescent probe for Hg2+ detection, DTPDI can be rapidly internalized into live cells with low cytotoxicity and high DNA delivery efficacy.
