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Updated: Dec 24, 2025

Fabrication of a Functionalized Magnetic Bacterial Nanocellulose with Iron Oxide Nanoparticles
Published on: May 26, 2016
Cellulose nanocrystals are effective in inhibiting host cell bacterial adhesion
G D'Orazio1, L Munizza, J Zampolli
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy. barbara.laferla@unimib.it patrizia.digennaro@unimib.it.
Abstract:
The use of cellulose nanocrystals (CNCs) as a biomaterial able to inhibit host cell bacterial adhesion is described. Pre-incubation of E. coli ATCC 25922 with a suspension of 0.1% CNCs afforded a significant 2 log reduction of bacterial adhesion to the intestinal cell monolayer HT29. This effect could be attributed to the interaction between the CNCs and the bacterial cell surface as confirmed using fluorescence microscopy experiments.
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