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Biofunctionalization of polydioxythiophene derivatives for biomedical applications
Xenofon Strakosas1, Bin Wei, David C Martin
1Bioelectronics, Ecole des Mines de St. Etienne, 880 Avenue de Mimet, Gardanne, France. owens@emse.fr.
Journal of Materials Chemistry. B
|April 9, 2020
Summary
Biofunctionalization of polydioxythiophenes (PEDOT and ProDOT) is crucial for advancing organic bioelectronics. This review highlights methods to improve their integration with biological systems for biosensing and cell interfacing.
Area of Science:
- Organic bioelectronics
- Polymer science
- Biomedical engineering
Background:
- Polydioxythiophenes like PEDOT and ProDOT are key materials in organic bioelectronics.
- Their pristine forms show promise but require biofunctionalization for broader applications.
- Biofunctionalization enhances the interface between biological and non-biological components.
Purpose of the Study:
- To review methods for biofunctionalizing polydioxythiophenes.
- To explore how synthesis methods impact biofunctionalization strategies.
- To highlight key biofunctionalization techniques for specific biomedical applications.
Main Methods:
- Chemical oxidative polymerization
- Vapor phase polymerization
- Direct electrochemical polymerization
- Review of existing biofunctionalization techniques
Main Results:
- Various biofunctionalization strategies exist for polydioxythiophenes.
- Synthesis methods influence the effectiveness of biofunctionalization.
- Specific examples demonstrate successful biofunctionalization for biomedical uses.
Conclusions:
- Biofunctionalization is essential for unlocking the full potential of polydioxythiophenes in bioelectronics.
- Future research should focus on novel biofunctionalization methods.
- Optimizing the bio-interface is critical for future advancements.
