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Predicting Body Mass Index From Structural MRI Brain Images Using a Deep Convolutional Neural Network.

Pál Vakli1, Regina J Deák-Meszlényi1, Tibor Auer2

  • 1Brain Imaging Centre, Research Centre for Natural Sciences, Budapest, Hungary.

Frontiers in Neuroinformatics
|April 9, 2020
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Summary

Deep learning accurately predicts body mass index (BMI) using structural brain scans. This neuroimaging approach reveals brain regions linked to BMI, offering new insights into body weight regulation.

Keywords:
amygdalabody mass indexcaudate nucleusconvolutional neural networksdeep learningmagnetic resonance imaging

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Area of Science:

  • Neuroimaging
  • Deep Learning
  • Human Physiology

Background:

  • Deep learning (DL) is increasingly utilized in cognitive and clinical neuroimaging.
  • DL models efficiently classify brain disorders and predict neurodegenerative disease risk.

Purpose of the Study:

  • To investigate the prediction of body mass index (BMI) using structural brain imaging and DL.
  • To explore the relationship between brain structure and individual BMI variations.

Main Methods:

  • A deep convolutional neural network (CNN) was employed to predict BMI.
  • The CNN utilized structural magnetic resonance imaging (MRI) brain scans, age, and sex as input data.
  • Localization maps were generated to identify brain regions contributing to BMI prediction.

Main Results:

  • Individual BMI was accurately predicted from single structural MRI scans using DL.
  • Key brain structures, including the caudate nucleus and amygdala, were identified as significant predictors of BMI.
  • CNN-based visualization provided complementary insights compared to standard brain segmentation methods.

Conclusions:

  • Predicting BMI from structural brain scans using DL is a promising approach.
  • This method can help investigate the link between brain morphology and body weight.
  • It opens new avenues for exploring the clinical utility of brain-predicted BMI.