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Updated: Dec 24, 2025

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
Published on: August 19, 2025
[Experiences with axillary reverse mapping].
Martinus A Beek1,2, Paul D Gobardhan3, Elisabeth G Klompenhouwer4
1AmphiaZiekenhuis, afd. Chirurgie, Breda.
Axillary reverse mapping (ARM) preserves upper extremity lymphatic drainage during lymph node dissection, significantly reducing postoperative symptoms like lymphoedema. This technique offers added value for patients undergoing axillary lymph node dissection.
Area of Science:
- Surgical Oncology
- Lymphedema Research
- Lymphatic System Imaging
Background:
- Axillary lymph node dissection (ALND) is a standard procedure for breast cancer staging.
- ALND can lead to significant postoperative morbidity, including lymphedema.
- Preserving lymphatic drainage is crucial for minimizing these complications.
Purpose of the Study:
- To evaluate the efficacy of Axillary Reverse Mapping (ARM) in preserving lymphatic channels and glands.
- To assess the impact of ARM on reducing postoperative symptoms following ALND.
- To determine the added value of ARM in patients undergoing ALND.
Main Methods:
- A randomized multicenter study was conducted.
- Axillary Reverse Mapping (ARM) technique was employed to map lymphatic drainage.
- Lymphatic channels and glands of the upper extremities were preserved during ALND in the intervention group.
Main Results:
- The study demonstrated statistically significant reductions in postoperative symptoms for patients who underwent ARM.
- Preservation of upper extremity lymphatics via ARM led to fewer adverse outcomes.
- ARM proved beneficial for patients requiring ALND.
Conclusions:
- Axillary Reverse Mapping (ARM) is an effective technique for preserving lymphatic function during ALND.
- ARM significantly decreases postoperative morbidity, particularly lymphoedema.
- ARM provides substantial benefits for patients undergoing ALND, despite its declining indication.
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