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Facilitated Transport01:19

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The chemical and physical properties of plasma membranes cause them to be selectively permeable. Since plasma membranes have both hydrophobic and hydrophilic regions, substances need to be able to transverse both regions. The hydrophobic area of membranes repels substances such as charged ions. Therefore, such substances need special membrane proteins to cross a membrane successfully. In  facilitated transport, also known as facilitated diffusion, molecules and ions travel across a...
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The chemical and physical properties of plasma membranes cause them to be selectively permeable. Since plasma membranes have both hydrophobic and hydrophilic regions, substances need to be able to transverse both regions. The hydrophobic area of membranes repels substances such as charged ions. Therefore, such substances need special membrane proteins to cross a membrane successfully. In  facilitated transport, also known as facilitated diffusion, molecules and ions travel across a...
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DNA replication is a well-evolved process that copies millions of base pairs with high fidelity during each cell division. Occasionally a wrong base or a long stretch of wrong bases may get added to the daughter strands. If the errors are left unchecked, cells might accumulate several mutations that might endanger their  survival. Therefore, the copying errors are checked and repaired at three levels.
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Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
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Cell sizes vary widely among and within organisms. Bacterial cells range between 1-10 micrometers (μm)and are considerably smaller than most eukaryotic cells. The smallest bacteria are 0.1 μm in diameter—about a thousand times smaller than eukaryotic cells, which typically range from 10-100 μm.
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Related Experiment Video

Updated: Dec 24, 2025

Adenofection: A Method for Studying the Role of Molecular Chaperones in Cellular Morphodynamics by Depletion-Rescue Experiments
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Author Correction: Hitchhiking into the cell.

Douglas B Kell1

  • 1Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool, UK. dbk@liv.ac.uk.

Nature Chemical Biology
|April 10, 2020
PubMed
Summary

This study has a published amendment. Please refer to the link at the top of the paper for the updated information and revised findings.

Area of Science:

  • Not specified in the abstract.

Background:

  • Not specified in the abstract.

Purpose of the Study:

  • Not specified in the abstract.

Main Methods:

  • Not specified in the abstract.

Main Results:

  • Not specified in the abstract.

Conclusions:

  • Not specified in the abstract.

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