Related Experiment Video
Updated: Dec 24, 2025

Purification and Transplantation of Myogenic Progenitor Cell Derived Exosomes to Improve Cardiac Function in Duchenne Muscular Dystrophic Mice
Published on: April 10, 2019
Duchenne Muscular Dystrophy: the Heart of the Matter
Jeffrey A Shih1, Alejandro Folch2, Brenda L Wong2
1University of Massachusetts, 55 Lake Avenue North, Worcester, MA, 01532, USA. jeffrey.shih@umassmemorial.org.
Purpose Of Review:
Duchenne muscular dystrophy is one of many neuromuscular disorders, but it frequently causes severe disability early in life and early death. Cardiac involvement is an important cause of morbidity and mortality.
Recent Findings:
Heart disease in Duchenne muscular dystrophy can include a cardiomyopathy leading to end-stage heart failure along with associated supraventricular and ventricular arrhythmias. This article reviews the diagnosis and treatment of heart disease in Duchenne muscular dystrophy as well as emerging therapies.
Related Concept Videos
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Satellite Stem Cells and Muscular Dystrophy
Cardiomyopathy I: Introduction and Classification
Cardiomyopathy V: Interprofessional Care
Cardiomyopathy IV: Restrictive Cardiomyopathy

