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Published on: January 28, 2020
Coronary Endarterectomy: a Case Control Study and Evaluation of Early Patency Rate of Endarterectomized Arteries
Mario Augusto Cray da Costa1,2, André Luís Betero3, Jefferson Okamoto3
1Universidade Estadual de Ponta Grossa Department of Medicine Ponta Grossa Paraná Brazil Department of Medicine, Universidade Estadual de Ponta Grossa - Campus Uvaranas, Ponta Grossa, Paraná, Brazil.
Insights
Coronary endarterectomy (CE) during coronary artery bypass grafting (CABG) shows similar graft patency, morbidity, and mortality rates compared to standard CABG. This procedure offers comparable outcomes despite longer procedure times.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery Outcomes
- Graft Patency
Background:
- Coronary artery bypass grafting (CABG) is a standard treatment for coronary artery disease.
- Coronary endarterectomy (CE) is a complementary procedure sometimes performed with CABG.
- The comparative outcomes of CABG with CE versus CABG alone require further investigation.
Purpose of the Study:
- To compare major and minor outcomes between patients undergoing CABG with CE and those undergoing CABG without CE.
- To evaluate early graft patency rates in patients who had CE.
- To assess the safety and efficacy of CE as an adjunct to CABG.
Main Methods:
- Retrospective review of a patient database from January 2011 to June 2017.
- Comparison of 25 patients who underwent CABG with CE against 201 patients who underwent CABG alone.
- Analysis of perioperative outcomes including myocardial infarction, stroke, mortality, cardiopulmonary bypass time, aortic clamp time, and hospital stay.
Main Results:
- No significant differences were observed in post-surgical hospitalization, perioperative myocardial infarction, stroke, or mortality rates.
- Coronary endarterectomy was associated with significantly longer aortic clamping and cardiopulmonary bypass times.
- Early graft patency in the CE group was 78.95%, consistent with existing literature.
Conclusions:
- Coronary endarterectomy, when performed with CABG, demonstrates early graft patency rates comparable to literature values.
- The addition of CE to CABG did not result in statistically significant differences in major adverse outcomes (morbidity and mortality) in this patient cohort.
- CE can be considered a viable option in selected cases, offering similar clinical outcomes to conventional CABG.
Objective:
To compare two groups of patients - the coronary endarterectomy group, with patients undergoing coronary artery bypass grafting (CABG) with coronary endarterectomy (CE), and the control group, with patients undergoing CABG without CE. We analyzed the rate of major outcomes (perioperative acute myocardial infarction [AMI], stroke, and mortality) and minor outcomes (time of cardiopulmonary bypass [CPB], time of aortic clamp, and postoperative length of hospital stay). We also determined the rates of early graft patency in patients undergoing CE.
Methods:
We reviewed a database of patients submitted to CABG, with or without associated CE, between January 2011 and June 2017. Twenty-five patients submitted to CE were compared with 201 patients submitted only to conventional surgery; the two groups presented similar preoperative characteristics and all the European System for Cardiac Operative Risk Evaluation (EuroSCORE) II variables did not presented statistically significant difference. We considered statistically significant values of P< 0.05.
Results:
There was no statistically significant difference in relation to time of post-surgical hospitalization (P=0.8139), incidence of perioperative AMI (P=0.2976), stroke (P=0,2976), and mortality rate (P=1.0000), but endarterectomy was associated with longer aortic clamping time (P=0.0004) and CPB time (P=0.0030). The rate of patency evaluated in patients submitted to endarterectomy (78,95%) was compatible with that described in the literature.
Conclusion:
In this sample, coronary endarterectomy was associated with the rate of early graft patency similar to that of the literature, with morbidity and mortality rates similar to those of conventional surgery.
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