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ANATOMICAL CHANGES ON SEQUENTIAL MULTIMODAL IMAGING IN PERIFOVEAL EXUDATIVE VASCULAR ANOMALOUS COMPLEX
Jennifer S N Verhoekx1, Lisette M Smid2, Koenraad A Vermeer2
1The Rotterdam Eye Hospital, Rotterdam, the Netherlands ; and.
Retina (Philadelphia, Pa.)
|April 10, 2020
Summary
Perifoveal exudative vascular anomalous complex (PEVAC) is a retinal vascular abnormality often linked to intraretinal cystic spaces. These spaces, and the PEVAC lesion itself, can resolve spontaneously over time.
Area of Science:
- Ophthalmology
- Retinal Vascular Diseases
- Medical Imaging
Background:
- Perifoveal exudative vascular anomalous complex (PEVAC) is an idiopathic retinal vascular abnormality.
- PEVAC is characterized by a large perifoveal vascular aneurysmal abnormality.
- Associated findings can include retinal hemorrhages and hard exudates.
Purpose of the Study:
- To describe a series of 21 patients diagnosed with PEVAC.
- To investigate the longitudinal anatomical changes associated with PEVAC lesions and related intraretinal cystic spaces.
Main Methods:
- Retrospective analysis of clinical data from patients presenting between 2014 and 2019.
- Data collection included best-corrected visual acuity, fundus photography, and various angiography techniques (OCT, OCT-A, fluorescein, indocyanine green).
Main Results:
- Twenty-one patients with PEVAC were analyzed with a mean follow-up of 24.3 months.
- Intraretinal cystic spaces on OCT were observed in 15 patients; 12 showed no changes, while 9 exhibited changes including spontaneous resolution.
- In 3 patients, the PEVAC lesion itself completely resolved spontaneously.
Conclusions:
- PEVAC is an idiopathic retinal vascular abnormality associated with intraretinal cystic spaces.
- Both the intraretinal cystic spaces and the PEVAC lesion demonstrate potential for spontaneous resolution.
- Intravitreal anti-VEGF treatment showed no improvement in patients with stable cystic spaces.
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