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Updated: Dec 24, 2025

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Advanced Black Phosphorus Nanomaterials for Bone Regeneration.

Yun'an Qing1, Ruiyan Li1, Shihuai Li1

  • 1Orthopaedic Medical Center, The Second Hospital of Jilin University, Changchun 130041, People's Republic of China.

International Journal of Nanomedicine
|April 11, 2020
PubMed
Summary

Black phosphorus (BP) nanomaterials show promise as graphene alternatives for bone regeneration due to their unique properties. This review highlights BP

Keywords:
2D materialsblack phosphorus nanomaterialsbone regenerationnanomedicine

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Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Regenerative Medicine

Background:

  • Bone regeneration is a significant clinical challenge.
  • Two-dimensional materials like graphene oxide are established for bone regeneration.
  • Black phosphorus (BP) nanomaterials emerged in 2014 as potential graphene substitutes.

Purpose of the Study:

  • To comprehensively review recent advances in black phosphorus (BP)-based nanomaterials for bone regeneration.
  • To summarize the advantages, synthesis methods, and applications of BP in promoting bone regeneration.
  • To discuss current challenges and future perspectives of BP in this field.

Main Methods:

  • Literature review of recent scientific advances.
  • Summary of black phosphorus (BP) synthesis methodologies.
  • Analysis of BP nanomaterial applications in bone regeneration studies.

Main Results:

  • BP nanomaterials possess excellent optical, mechanical, electrical, biocompatibility, and biodegradation properties.
  • BP nanomaterials are attractive for biomedical applications, including bone regeneration.
  • Various synthesis methods for BP nanomaterials have been developed.

Conclusions:

  • Black phosphorus (BP) nanomaterials offer significant advantages over traditional materials for bone regeneration.
  • Further research into BP's challenges and applications is warranted for clinical translation.
  • BP nanomaterials represent a promising frontier in regenerative medicine for skeletal repair.